Interpretive description is a research strategy which guides researchers through all the phases of a qualitative research process. The strategy acknowledges object neutrality and object theorizing as components of equal importance and value in the production of results which are academically credible and clinically practical. In this article, we introduce interpretive description and outline the steps of conceiving, designing, and implementing coherent research capable of generating new insight into clinical settings. We focus on the theoretical account as well as the practical implementation and briefly discuss the possibilities and limitations of the strategy of studying clinical problems.